August 18, 2015

mBio (2015) "Remodeling of the Z-ring nanostructure during the Streptococcus pneumoniae cell cycle revealed by photoactivated localization microscopy"

Ovococci form a morphological group that includes several human pathogens (enterococci and streptococci). Their shape r...

January 16, 2015

Methods Appl. Fluoresc. (2015) "Rational design of enhanced photoresistance in a photoswitchable fluorescent protein"

Fluorescent proteins are particularly susceptible to photobleaching, the permanent loss of fluorescence emission resulting from photodestruction of the...

November 6, 2013

We deposited three new structures of IrisFP  bleached in anaerobic conditions, bleached by X-rays and bleached in aerobic conditions (PDB ID: 4LJB, 4LJC and 4LJD, respectively). These new structures demonstrate the two photobleaching pathways of fluorescent proteins we...

October 23, 2013

J. Am. Chem. Soc (2013) "Structural evidence for a two-regime photobleaching mechanism in a reversibly switchable fluorescent protein"

Photobleaching, the irreversible photodestruction of a chromophore, severely limits the use of fluorescent proteins (FPs) in optical mi...

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