September 6, 2017

J Phys Chem Lett (2017) "Photoswitching of green mEos2 by intense 561 nm light perturbs efficient green-to-red photoconversion in localization microscopy"

Green-to-red photoconvertible fluorescent proteins (PCFPs) such as mEos2 and its derivatives are widely used in Pho...

January 21, 2016

J Am Chem Soc (2016) "Arginine 66 controls dark-state formation in green-to-red photoconvertible fluorescent proteins"

Photoactivated localization microscopy (PALM) is a powerful technique to investigate cellular nanostructures quantitatively and dynamically. However, t...

August 18, 2015

mBio (2015) "Remodeling of the Z-ring nanostructure during the Streptococcus pneumoniae cell cycle revealed by photoactivated localization microscopy"

Ovococci form a morphological group that includes several human pathogens (enterococci and streptococci). Their shape r...

January 16, 2015

Methods Appl. Fluoresc. (2015) "Rational design of enhanced photoresistance in a photoswitchable fluorescent protein"

Fluorescent proteins are particularly susceptible to photobleaching, the permanent loss of fluorescence emission resulting from photodestruction of the...

October 23, 2013

J. Am. Chem. Soc (2013) "Structural evidence for a two-regime photobleaching mechanism in a reversibly switchable fluorescent protein"

Photobleaching, the irreversible photodestruction of a chromophore, severely limits the use of fluorescent proteins (FPs) in optical mi...

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