I am a research scientist for the CNRS (Centre National de la Recherche Scientifique) working at the Institute for Structural Biology (IBS) in Grenoble, France.


My research interest in the PIXEL team is centered on the engineering and characterization of fluorescent proteins, using a set of techniques: molecular biology, biochemistry, kinetic X-ray crystallography, spectroscopy and single-molecule localization microscopy.


On this website, you will find all relevant information about my work-related activities: from my CV, including the list of my publications and my Ph.D. thesis to details about my past and current research projectsA list of my deposited 3D atomic structures is available as well as a selection of videos representative of my research career. You can also consult my presentations  (conferences & posters), public communication actions and teaching experience. Awards I received and coverage of some results by media are detailed on dedicated pages.


Would you have some questions or requests, please contact me or leave a comment or/and connect to any professional network by clicking on the icons at the bottom of each page.

May 28, 2020

J Am Chem Soc (2020) "Mechanistic investigations of green mEos4b reveal a dynamic long-lived dark state"

Green-to-red photoconvertible fluorescent proteins (PCFPs) are key players in advanced microscopy schemes such as photoactivated localization microscopy (PALM). Whereas photoconversion and red-state blinking in PCFPs have been studied intensively, their green-state photophysical behavior has received less attention. Yet dark states in green PCFPs can become strongly populated in PALM schemes and exert an indirect but considerable influence on the quality of data recorded in the red channel. Furthermore, green-state photoswitching in PCFPs can be used directly for PALM and has been engineered to design highly efficient reversibly switchable fluoresc...

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