Welcome!

 

I am a research scientist for the CNRS (Centre National de la Recherche Scientifique) working at the Institute for Structural Biology (IBS) in Grenoble, France.

 

My research interest in the PIXEL team is centered on the engineering and characterization of fluorescent proteins, using a set of techniques: molecular biology, biochemistry, kinetic X-ray crystallography, spectroscopy and single-molecule localization microscopy.

 

On this website, you will find all relevant information about my work-related activities: from my CV, including the list of my publications and my Ph.D. thesis to details about my past and current research projectsA list of my deposited 3D atomic structures is available as well as a selection of videos representative of my research career. You can also consult my presentations  (conferences & posters), public communication actions and teaching experience. Awards I received and coverage of some results by media are detailed on dedicated pages.

 

Would you have some questions or requests, please contact me or leave a comment or/and connect to any professional network by clicking on the icons at the bottom of each page.

December 3, 2019

Biophys J (2019) "NMR reveals light-induced changes in the dynamics of a photoswitchable fluorescent protein"

The availability of fluorescent proteins with distinct phototransformation properties is crucial for a wide range of applications in advanced fluorescence microscopy and biotechnology. To rationally design new variants optimized for specific applications, a detailed understanding of the mechanistic features underlying phototransformation is essential. At present, little is known about the conformational dynamics of fluorescent proteins at physiological temperature and how these dynamics contribute to the observed phototransformation properties. Here, we apply high-resolution NMR spectroscopy in solution combined with in situ sample illuminatio...

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